IndirizzoDescrizione del lavoro:
Posting Title: Master's Thesis Protein Production, Purification & Analysis Intern
Help us get ahead of disease together with our Protein Production, Purification & Analysis Team
Education required: Scientific degree in biotechnology, microbiology and biochemistry
Other requirements:
* Written and spoken fluency in English and Italian
* Sound scientific methodology, critical thinking, and problem-solving skills
* Basic expression and purification techniques
* Ability to make molarity calculations for the preparation of solutions and buffers and for diluting, quantifying and dispensing proteic material
Application deadline: February 22nd
Duration: 6 Months + 6 Months
Start date: April 2024
Type: Curricular Internship
Looking to gain valuable real world work experience and help positively impact the health of billions of people? Apply for a (COMPANY NAME) Internship today!
A (COMPANY NAME) internship offers you the opportunity to kickstart your career - to take on a real role with genuine impact! You'll take on challenging, serious work on live projects or assignments. You'll also get to learn from us, develop your skills and gain valuable experience for wherever the future takes you.
What will you do?
Context
Fermentation, protein purification and analytics team (FPPA lab) operating within the Antigen Design function in Research department is mainly involved in the production, purification, analytical and functional characterization of novel proteic vaccine candidates with the perspective of process transfer at manufacturing scale.
The intern will initially be supported by experienced scientists of the laboratory to learn the fermentation and chromatographic techniques necessary for the production and the purification of the antigen of interest.
Project intern description
The project has the objective to exploit the Production of Bacterial Cell Membrane proteins with different approaches with a special focus on cell free-system technology. The candidate will first produce the bacterial Membrane Proteins and after partial purification he/she will evaluate the chemical-physical properties of the produced proteins, manly focusing on their folding, thermal stability and capability to bind specific and functional monoclonal antibodies. Bacterial Membrane Proteins will be selected from Neisseria Gonorreae, Chlamydia Trachomatis and E. coli genomes.
Competencies the intern will develop thanks to the internship experience
Learn and understand the available techniques for Membrane Proteins analytical characterization. In particular, the student will learn how to express in-vitro proteins, chromatographic techniques, SE-HPLC, SDS-page, western blot, quantification methods, thermal stability analysis, SPR and BLI technics. All these techniques will allow him/her to produce and characterize bacterial Membrane Proteins that can be used to solve its structure and consequently better understand the role of the candidate during bacterial infection.
Let's do this!
You'll find hints, tips and guidance on our recruitment process on our website -
Learn more about the application process | (COMPANY NAME)
We recommend you apply as soon as possible, because we accept ongoing applications and offer positions on a first come, first served basis.
Apply now!
Need help with your application?
Please email us at ww.earlytalentrecruitment@(COMPANY NAME).com and let us know how we can help you.
Why Us?
(COMPANY NAME) is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making (COMPANY NAME) a place where people can thrive. We want (COMPANY NAME) to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our (COMPANY NAME) leadership reflects our (COMPANY NAME) workforce.
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(COMPANY NAME) is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
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